A Comparison of Methylphenidate (MPH) and Combined Methylphenidate with Crocus sativus (Saffron) in the Treatment of Children and Adolescents with ADHD: A Randomized, Double-blind, Parallel-Group, Clinical Trial
نویسندگان
چکیده
Background: Attention-deficit/hyperactivity disorder (ADHD) is characterized by behavioral and neurodevelopmental problems. It estimated that 3 - 7% of children adolescents suffer from this problem. Apart synthetic drugs, other effective types medication like herbal medicines are great importance. Objectives: This study aimed to evaluate the effectiveness methylphenidate (MPH) its combination with Crocus sativus (saffron) in treatment suffering ADHD. Methods: The sample included 70 aged between 6 16 years who had been diagnosed patients were randomly assigned into two equal groups (n = 35 each group). While both received 20 or 30 mg/d MPH (20 for < > 30, respectively), one them also saffron a capsule based on BMI respectively). To collect data, parents teachers completed Attention-Deficit/Hyperactivity Disorder Rating Scale-IV (ADHD-RS-IV). Also, analyzing repeated measures analysis variance (RMANOVA) was used. Results: results general linear model (GLM) indicated groups, less symptoms after eight weeks treatment. However, four weeks, average score group lower than total (P 0.05). Conclusions: Using combined proved be more ADHD compared separate treatments. seems duration therapy can reduced improved prescribing proposed
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ژورنال
عنوان ژورنال: Iranian journal of psychiatry and behavioral sciences
سال: 2021
ISSN: ['1735-8639', '1735-9287']
DOI: https://doi.org/10.5812/ijpbs.108390